Negligible senescence is a term coined by biogerontologist Caleb Finch
to denote organisms that do not exhibit evidence of biological aging
(senescence), such as measurable reductions in their reproductive
capability, measurable functional decline, or rising death rates with
age. There are many species where scientists have seen no increase in
mortality after maturity. This may mean that the lifespan of the
organism is so long that researchers' subjects have not yet lived up
to the time when a measure of the species' longevity can be made.
Turtles, for example, were once thought to lack senescence, but more
extensive observations have found evidence of decreasing fitness with
age.Study of negligibly senescent animals may provide clues that lead
to better understanding of the aging process and influence theories of
aging. The phenomenon of negligible senescence in some animals is a
traditional argument for attempting to achieve similar negligible
senescence in humans by technological means.There are also
organisms[which?] that exhibit negative senescence, whereby mortality
chronologically decreases as the organism ages, for all or part of the
life cycle, in disagreement with the Gompertzâ€"Makeham law of
mortality (see also Late-life mortality deceleration). Furthermore,
there are species that have been observed to regress to a larval state
and regrow into adults multiple times, such as Turritopsis
dohrnii.Studies have indicated a connection between phenomena related
to negligible senescence and the general stability of an organism's
genome over its lifetime.
to denote organisms that do not exhibit evidence of biological aging
(senescence), such as measurable reductions in their reproductive
capability, measurable functional decline, or rising death rates with
age. There are many species where scientists have seen no increase in
mortality after maturity. This may mean that the lifespan of the
organism is so long that researchers' subjects have not yet lived up
to the time when a measure of the species' longevity can be made.
Turtles, for example, were once thought to lack senescence, but more
extensive observations have found evidence of decreasing fitness with
age.Study of negligibly senescent animals may provide clues that lead
to better understanding of the aging process and influence theories of
aging. The phenomenon of negligible senescence in some animals is a
traditional argument for attempting to achieve similar negligible
senescence in humans by technological means.There are also
organisms[which?] that exhibit negative senescence, whereby mortality
chronologically decreases as the organism ages, for all or part of the
life cycle, in disagreement with the Gompertzâ€"Makeham law of
mortality (see also Late-life mortality deceleration). Furthermore,
there are species that have been observed to regress to a larval state
and regrow into adults multiple times, such as Turritopsis
dohrnii.Studies have indicated a connection between phenomena related
to negligible senescence and the general stability of an organism's
genome over its lifetime.
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